| 1. Round | 29/07/2016 | KV Mechelen | - | Club Brugge KV | 0:2 | ||||
| 2. Round | 06/08/2016 | KAS Eupen | - | KV Mechelen | 0:2 | ||||
| 3. Round | 13/08/2016 | KV Mechelen | - | KV Kortrijk | 0:0 | ||||
| 4. Round | 20/08/2016 | Waasland-Beveren | - | KV Mechelen | 2:2 | ||||
| 5. Round | 27/08/2016 | KVC Westerlo | - | KV Mechelen | 1:2 |  |
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| 6. Round | 10/09/2016 | KV Mechelen | - | Sint-Truidense VV | 2:0 | ||||
| 7. Round | 16/09/2016 | Sporting Charleroi | - | KV Mechelen | 0:0 | ||||
| 8. Round | 24/09/2016 | KV Mechelen | - | SV Zulte Waregem | 2:3 | ||||
| 9. Round | 02/10/2016 | KRC Genk | - | KV Mechelen | 2:1 | ||||
| 10. Round | 16/10/2016 | KV Mechelen | - | KV Oostende | 2:3 | ||||
| 11. Round | 22/10/2016 | KV Mechelen | - | Royal Excel Mouscron | 2:0 | ||||
| 12. Round | 26/10/2016 | RSC Anderlecht | - | KV Mechelen | 2:0 |
Belgium