| 14. Round | 27/06/2021 | Rukh Brest | - | FK Slutsk | 1:0 | ||||
| 15. Round | 03/07/2021 | FK Slutsk | - | Sputnik Rechytsa | 3:2 |  |
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| 16. Round | 16/07/2021 | FK Slutsk | - | BATE Borisov | 3:4 | ||||
| 17. Round | 24/07/2021 | Neman Grodno | - | FK Slutsk | 1:0 | ||||
| 18. Round | 01/08/2021 | FK Slutsk | - | Dinamo Minsk | 1:1 | ||||
| 19. Round | 14/08/2021 | Torpedo-BelAZ Zhodino | - | FK Slutsk | 0:1 | ||||
| 20. Round | 20/08/2021 | FK Slutsk | - | FK Vitebsk | 1:2 | ||||
| 21. Round | 29/08/2021 | FK Slutsk | - | FK Slaviya Mozyr | 2:1 | ||||
| 22. Round | 11/09/2021 | Dinamo Brest | - | FK Slutsk | 0:0 | ||||
| 23. Round | 18/09/2021 | FK Slutsk | - | FK Gomel | 1:4 | ||||
| 24. Round | 25/09/2021 | FK Minsk | - | FK Slutsk | 2:1 | |
Belarus