5. Round | 15/08/2021 | Municipal Pérez Zeledón | - | Guadalupe | 1:1 | ||||
6. Round | 17/08/2021 | Municipal Grecia | - | Municipal Pérez Zeledón | 1:0 | ||||
7. Round | 24/08/2021 | AD Guanacasteca | - | Municipal Pérez Zeledón | 2:1 | ||||
17. Round | 23/10/2021 | Municipal Pérez Zeledón | - | Municipal Grecia | 3:1 | ![]() |
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18. Round | 28/10/2021 | Municipal Pérez Zeledón | - | AD Guanacasteca | 2:0 | ||||
19. Round | 30/10/2021 | Santos de Guápiles | - | Municipal Pérez Zeledón | 3:2 | ||||
20. Round | 20/11/2021 | Municipal Pérez Zeledón | - | CS Cartaginés | 3:0 | ![]() |
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21. Round | 23/11/2021 | Municipal Pérez Zeledón | - | Sporting FC | 1:0 | ![]() |
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22. Round | 28/11/2021 | LD Alajuelense | - | Municipal Pérez Zeledón | 3:0 | ![]() |