| 2. Round | 28/10/2021 | ES Métlaoui | - | US Ben Guerdane | 0:0 | ||||
| 3. Round | 31/10/2021 | US Ben Guerdane | - | CS Sfaxien | 0:1 | ||||
| 4. Round | 03/11/2021 | US Ben Guerdane | - | Espérance de Tunis | 0:0 |  |
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| 5. Round | 06/11/2021 | US Tataouine | - | US Ben Guerdane | 1:2 |  |
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| 6. Round | 18/11/2021 | US Ben Guerdane | - | ES Hammam Sousse | 2:1 | ||||
| 7. Round | 21/11/2021 | CA Bizertin | - | US Ben Guerdane | 1:2 | ||||
| 8. Round | 20/02/2022 | CS Hammam-Lif | - | US Ben Guerdane | 0:0 | ||||
| 9. Round | 27/02/2022 | US Ben Guerdane | - | ES Métlaoui | 1:0 |  |
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| 10. Round | 09/03/2022 | CS Sfaxien | - | US Ben Guerdane | 0:1 | ||||
| 11. Round | 16/03/2022 | Espérance de Tunis | - | US Ben Guerdane | 0:0 | ||||
| 13. Round | 10/04/2022 | ES Hammam Sousse | - | US Ben Guerdane | 1:1 | ||||
| 14. Round | 18/04/2022 | US Ben Guerdane | - | CA Bizertin | 0:1 |
Tunisia