| 1. Round | 06/08/2005 | Sint-Truidense VV | - | KSV Roeselare | 1:0 | ||||
| 2. Round | 14/08/2005 | KSV Roeselare | - | KSK Beveren | 1:0 | ||||
| 3. Round | 20/08/2005 | Club Brugge KV | - | KSV Roeselare | 1:0 | ||||
| 4. Round | 28/08/2005 | KSV Roeselare | - | Sporting Lokeren | 4:0 |  |
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| 10. Round | 15/10/2005 | KSV Roeselare | - | RAA La Louviére | 4:1 | ||||
| 12. Round | 30/10/2005 | KSV Roeselare | - | Germinal Beerschot | 5:1 | ||||
| 13. Round | 05/11/2005 | KRC Genk | - | KSV Roeselare | 4:1 | ||||
| 15. Round | 14/12/2005 | FC Brussels | - | KSV Roeselare | 1:0 |
Belgium