| 22. Round | 14/01/2022 | NAC Breda | - | FC Volendam | 0:0 | ||||
| 23. Round | 21/01/2022 | MVV | - | FC Volendam | 0:1 | ||||
| 25. Round | 04/02/2022 | FC Volendam | - | FC Utrecht (J) | 2:0 | ||||
| 24. Round | 07/02/2022 | Roda JC Kerkrade | - | FC Volendam | 1:1 | ||||
| 26. Round | 11/02/2022 | FC Volendam | - | AZ Alkmaar (J) | 2:1 | ||||
| 28. Round | 25/02/2022 | FC Volendam | - | Helmond Sport | 4:1 | ||||
| 29. Round | 04/03/2022 | VVV-Venlo | - | FC Volendam | 0:0 | ||||
| 33. Round | 01/04/2022 | FC Volendam | - | TOP Oss | 1:2 | ||||
| 35. Round | 16/04/2022 | FC Volendam | - | Jong Ajax | 3:1 |
Netherlands