| 1. Round | 18/07/2021 | Sport Boys | - | Cienciano | 1:4 | ||||
| 5. Round | 08/08/2021 | Academia Cantolao | - | Sport Boys | 0:2 | ||||
| 6. Round | 15/08/2021 | Sport Boys | - | Universidad San Martín | 2:0 | ||||
| 8. Round | 22/08/2021 | Sport Boys | - | Universitario de Deportes | 0:0 | ||||
| 9. Round | 29/08/2021 | Sport Huancayo | - | Sport Boys | 1:1 | ||||
| 7. Round | 03/09/2021 | Deportivo Municipal | - | Sport Boys | 0:1 |  |
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| 10. Round | 13/09/2021 | Sport Boys | - | Universidad Cesar Vallejo | 2:2 | ||||
| 15. Round | 16/10/2021 | Universidad Técnica | - | Sport Boys | 1:1 | ||||
| 16. Round | 22/10/2021 | Sport Boys | - | Mannucci | 3:3 |
Peru