| 4. Round | 28/08/2021 | Swift Hesperange | - | Etzella Ettelbruck | 5:2 |  |
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| 5. Round | 12/09/2021 | FC Differdange 03 | - | Swift Hesperange | 0:0 | ||||
| 6. Round | 18/09/2021 | Swift Hesperange | - | Victoria Rosport | 1:1 |  |
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| 8. Round | 26/09/2021 | Swift Hesperange | - | UNA Strassen | 0:1 | ||||
| 11. Round | 05/11/2021 | Swift Hesperange | - | RM Hamm Benfica | 7:0 | ||||
| 29. Round | 15/05/2022 | US Hostert | - | Swift Hesperange | 1:3 | ||||
| 30. Round | 22/05/2022 | Swift Hesperange | - | RFCU Luxemburg | 2:0 |
Ghana