| 11. Round | 01/10/2020 | Real Estelí FC | - | Chinandega | 3:0 | ||||
| 12. Round | 19/10/2020 | Real Madriz | - | Real Estelí FC | 1:0 | ||||
| 13. Round | 24/10/2020 | Real Estelí FC | - | Juventus Managua | 3:0 |  |
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| 14. Round | 29/10/2020 | ART Municipal Jalapa | - | Real Estelí FC | 1:0 | ||||
| 15. Round | 31/10/2020 | Real Estelí FC | - | CD Walter Ferretti | 1:1 | ||||
| 16. Round | 09/11/2020 | Diriangén FC | - | Real Estelí FC | 2:2 | ||||
| 17. Round | 15/11/2020 | Real Estelí FC | - | Junior Managua | 1:1 |  |
Brazil