| 1. Round | 10/08/2015 | Leicester City U21 | - | Manchester United U21 | 1:1 | ||||
| 5. Round | 21/09/2015 | Manchester United U21 | - | Everton FC U21 | 3:1 | ||||
| 8. Round | 26/10/2015 | Sunderland AFC U21 | - | Manchester United U21 | 0:1 | ||||
| 10. Round | 23/11/2015 | Norwich City U21 | - | Manchester United U21 | 2:0 | ||||
| 11. Round | 30/11/2015 | Manchester United U21 | - | Liverpool FC U21 | 3:2 | ||||
| 21. Round | 04/04/2016 | Manchester United U21 | - | Chelsea FC U21 | 1:1 | ||||
| 2. Round | 11/04/2016 | Manchester United U21 | - | Middlesbrough FC U21 | 1:0 | ||||
| 6. Round | 19/04/2016 | Tottenham Hotspur U21 | - | Manchester United U21 | 2:3 | ||||
| 22. Round | 25/04/2016 | Southampton FC U21 | - | Manchester United U21 | 2:1 |
England