| 2. Round | 08/10/2020 | Honduras Progreso | - | Vida | 1:1 | ||||
| 3. Round | 11/10/2020 | Vida | - | Marathón | 0:1 | ||||
| 4. Round | 15/10/2020 | Vida | - | Real Sociedad | 1:0 | ||||
| 5. Round | 19/10/2020 | Real España | - | Vida | 0:3 | ||||
| 7. Round | 25/10/2020 | Vida | - | Honduras Progreso | 4:1 | ||||
| 8. Round | 28/10/2020 | Marathón | - | Vida | 0:2 | ||||
| 9. Round | 02/11/2020 | Real Sociedad | - | Vida | 1:6 | ||||
| 13. Round | 15/11/2020 | Motagua | - | Vida | 3:0 | ||||
| 10. Round | 21/11/2020 | Vida | - | Real España | 2:2 |  |
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| 11. Round | 26/11/2020 | Olimpia | - | Vida | 1:0 | ||||
| 12. Round | 28/11/2020 | Vida | - | Real de Minas | 3:1 |
Honduras