| 5. Round | 30/07/2022 | Jaguares de Córdoba | - | Alianza Petrolera | 2:1 | ||||
| 6. Round | 06/08/2022 | Deportes Tolima | - | Jaguares de Córdoba | 2:2 | ||||
| 8. Round | 21/08/2022 | Millonarios | - | Jaguares de Córdoba | 2:0 | ||||
| 10. Round | 06/09/2022 | Deportivo Pasto | - | Jaguares de Córdoba | 2:1 | ||||
| 11. Round | 11/09/2022 | Jaguares de Córdoba | - | Atlético Nacional | 0:1 | ||||
| 12. Round | 18/09/2022 | Unión Magdalena | - | Jaguares de Córdoba | 1:0 |  |
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| 13. Round | 21/09/2022 | Jaguares de Córdoba | - | Atlético Bucaramanga | 0:1 | ||||
| 15. Round | 01/10/2022 | Once Caldas | - | Jaguares de Córdoba | 0:1 | |
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| 16. Round | 08/10/2022 | Jaguares de Córdoba | - | La Equidad | 1:1 | ||||
| 17. Round | 13/10/2022 | América de Cali | - | Jaguares de Córdoba | 1:1 | ||||
| 18. Round | 17/10/2022 | Jaguares de Córdoba | - | Santa Fe | 2:1 | ||||
| 19. Round | 23/10/2022 | Independiente Medellín | - | Jaguares de Córdoba | 0:0 | ||||
| 20. Round | 30/10/2022 | Jaguares de Córdoba | - | Atlético Junior | 0:2 | |
Colombia