| 1. Round | 27/02/2022 | Zulia FC | - | Deportivo Lara | 0:1 | ||||
| 2. Round | 05/03/2022 | Deportivo Táchira | - | Zulia FC | 3:0 | ||||
| 3. Round | 11/03/2022 | Zulia FC | - | Metropolitanos FC | 1:2 | ||||
| 5. Round | 24/03/2022 | Zulia FC | - | Deportivo La Guaira | 0:2 | ||||
| 6. Round | 02/04/2022 | Aragua FC | - | Zulia FC | 0:0 |  |
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| 8. Round | 14/04/2022 | Zulia FC | - | Universidad Central | 2:2 |
Venezuela