| 2. Round | 20/08/2021 | Sliema Wanderers | - | Floriana FC | 0:0 | ||||
| 3. Round | 11/09/2021 | Gżira United | - | Sliema Wanderers | 1:1 | ||||
| 8. Round | 31/10/2021 | Sliema Wanderers | - | Mosta FC | 2:3 | ||||
| 10. Round | 27/11/2021 | Birkirkara FC | - | Sliema Wanderers | 2:0 | ||||
| 11. Round | 05/12/2021 | Sliema Wanderers | - | Hamrun Spartans | 0:2 |
USA
Mexico