| 1. Round | 01/02/2025 | Atlético FC | - | Barranquilla FC | 1:2 | ||||
| 2. Round | 10/02/2025 | Barranquilla FC | - | Real Santander | 1:2 | ||||
| 3. Round | 17/02/2025 | Patriotas FC | - | Barranquilla FC | 1:0 | ||||
| 4. Round | 24/02/2025 | Barranquilla FC | - | Leones FC | 2:3 | ||||
| 6. Round | 08/03/2025 | Orsomarso SC | - | Barranquilla FC | 3:0 | ||||
| 7. Round | 18/03/2025 | Barranquilla FC | - | Jaguares de Córdoba | 0:1 |  |
|||
| 8. Round | 25/03/2025 | Internacional de Palmira | - | Barranquilla FC | 3:0 | ||||
| 9. Round | 29/03/2025 | Barranquilla FC | - | Real Cartagena | 2:2 | ||||
| 10. Round | 06/04/2025 | Cúcuta Deportivo | - | Barranquilla FC | 4:1 | ||||
| 11. Round | 12/04/2025 | Barranquilla FC | - | Bogotá FC | 2:0 | ||||
| 12. Round | 17/04/2025 | Real Soacha Cundinamarca | - | Barranquilla FC | 2:0 | ||||
| 5. Round | 24/04/2025 | Barranquilla FC | - | Deportes Quindío | 1:1 | ||||
| 14. Round | 07/05/2025 | Real Cartagena | - | Barranquilla FC | 3:0 |
Colombia