| 1. Round | 16/05/2021 | Cerrito | - | River Plate | 3:1 |  |
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| 2. Round | 22/05/2021 | Cerro Largo | - | Cerrito | 3:1 | |
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| 5. Round | 12/06/2021 | Cerrito | - | Plaza Colonia | 1:2 | ||||
| 6. Round | 18/06/2021 | Fénix | - | Cerrito | 1:3 | ||||
| 7. Round | 22/06/2021 | Cerrito | - | Boston River | 1:0 | |
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| 8. Round | 29/06/2021 | Montevideo Wanderers | - | Cerrito | 1:0 | ||||
| 9. Round | 05/07/2021 | Cerrito | - | Rentistas | 0:1 | |
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| 10. Round | 12/07/2021 | Peñarol | - | Cerrito | 2:0 |
Uruguay