| 2. Round | 06/08/2022 | Cerrito | - | Boston River | 0:3 | ||||
| 3. Round | 11/08/2022 | Deportivo Maldonado | - | Cerrito | 2:1 |  |
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| 6. Round | 20/08/2022 | Cerrito | - | Cerro Largo | 0:0 |  |
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| 7. Round | 09/09/2022 | Liverpool | - | Cerrito | 3:0 | ||||
| 8. Round | 15/09/2022 | Cerrito | - | Fénix | 0:2 | ||||
| 9. Round | 18/09/2022 | Peñarol | - | Cerrito | 3:1 | |
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| 10. Round | 26/09/2022 | Cerrito | - | Defensor Sporting | 1:2 | ||||
| 12. Round | 08/10/2022 | Cerrito | - | Albion | 0:0 | ||||
| 13. Round | 14/10/2022 | Montevideo Wanderers | - | Cerrito | 2:1 | ||||
| 14. Round | 18/10/2022 | Cerrito | - | Nacional | 1:2 | ||||
| 15. Round | 23/10/2022 | Plaza Colonia | - | Cerrito | 1:3 |  |
Uruguay