| 1. Round | 04/10/2020 | Vida | - | Platense | 3:3 |  |
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| 2. Round | 08/10/2020 | Honduras Progreso | - | Vida | 1:1 | ||||
| 3. Round | 11/10/2020 | Vida | - | Marathón | 0:1 | |
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| 4. Round | 15/10/2020 | Vida | - | Real Sociedad | 1:0 | ||||
| 5. Round | 19/10/2020 | Real España | - | Vida | 0:3 | ||||
| 7. Round | 25/10/2020 | Vida | - | Honduras Progreso | 4:1 | ||||
| 8. Round | 28/10/2020 | Marathón | - | Vida | 0:2 | ||||
| 9. Round | 02/11/2020 | Real Sociedad | - | Vida | 1:6 | ||||
| 13. Round | 15/11/2020 | Motagua | - | Vida | 3:0 | ||||
| 10. Round | 21/11/2020 | Vida | - | Real España | 2:2 | |
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| 12. Round | 28/11/2020 | Vida | - | Real de Minas | 3:1 |  |
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| 6. Round | 07/12/2020 | Platense | - | Vida | 1:0 | ||||
| 14. Round | 12/12/2020 | Vida | - | Lobos UPNFM | 0:3 |
Honduras