| Group B | 15/10/2022 | Atlético Huila | - | Deportes Quindío | 2:1 |  |
 |
||
| Group B | 21/10/2022 | Deportes Quindío | - | Real Santander | 1:0 | |
|||
| Group B | 30/10/2022 | Tigres FC | - | Deportes Quindío | 1:2 | ||||
| Group B | 03/11/2022 | Real Santander | - | Deportes Quindío | 3:2 | ||||
| Group B | 08/11/2022 | Deportes Quindío | - | Atlético Huila | 3:0 | |
Colombia