| 4. Round | 15/07/2022 | Jorge Wilstermann | - | CD Guabirá | 2:2 | ||||
| 5. Round | 26/07/2022 | Bolívar | - | Jorge Wilstermann | 3:0 | ||||
| 10. Round | 14/08/2022 | Nacional Potosí | - | Jorge Wilstermann | 1:0 | ||||
| 11. Round | 21/08/2022 | Jorge Wilstermann | - | Universitario de Sucre | 5:1 | ||||
| 12. Round | 25/08/2022 | Always Ready | - | Jorge Wilstermann | 2:1 | ||||
| 19. Round | 01/10/2022 | CD Guabirá | - | Jorge Wilstermann | 1:1 |  |
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| 20. Round | 05/10/2022 | Jorge Wilstermann | - | Bolívar | 1:1 | ||||
| 21. Round | 10/10/2022 | Jorge Wilstermann | - | Blooming | 1:0 | ||||
| 22. Round | 14/10/2022 | Real Tomayapo | - | Jorge Wilstermann | 1:0 | ||||
| 23. Round | 17/10/2022 | Jorge Wilstermann | - | Independiente Petrolero | 1:3 | ||||
| 24. Round | 22/10/2022 | Oriente Petrolero | - | Jorge Wilstermann | 2:1 |
Bolivia