| 5. Round | 24/08/2024 | Marathón | - | Real España | 0:1 | ||||
| 7. Round | 15/09/2024 | Juticalpa | - | Real España | 0:1 | ||||
| 8. Round | 20/09/2024 | Real España | - | Victoria | 1:1 | ||||
| 9. Round | 23/09/2024 | Lobos UPNFM | - | Real España | 1:0 |  |
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| 11. Round | 07/10/2024 | Motagua | - | Real España | 0:4 | ||||
| 12. Round | 21/10/2024 | Real España | - | Olancho FC | 1:1 | ||||
| 13. Round | 27/10/2024 | Deportivo Génesis | - | Real España | 1:1 | ||||
| 14. Round | 03/11/2024 | Real España | - | Marathón | 0:3 | ||||
| 15. Round | 07/11/2024 | Olimpia | - | Real España | 1:0 |
Panama