| 19. Round | 12/01/2022 | Persiraja Banda Aceh | - | PSIS Semarang | 0:1 | ||||
| 20. Round | 17/01/2022 | PSIS Semarang | - | Arema Cronus FC | 0:0 | ||||
| 21. Round | 28/01/2022 | Madura United | - | PSIS Semarang | 2:1 |  |
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| 24. Round | 10/02/2022 | PSIS Semarang | - | PS Barito Putera | 1:2 | ||||
| 25. Round | 15/02/2022 | Persib Bandung | - | PSIS Semarang | 0:0 | ||||
| 26. Round | 20/02/2022 | PSIS Semarang | - | Bali United | 0:1 | ||||
| 27. Round | 24/02/2022 | Borneo FC | - | PSIS Semarang | 1:1 | ||||
| 28. Round | 28/02/2022 | PSIS Semarang | - | Persikabo 1973 | 1:0 | ||||
| 29. Round | 06/03/2022 | PSM Makassar | - | PSIS Semarang | 2:1 | ||||
| 30. Round | 12/03/2022 | PSIS Semarang | - | Bhayangkara Presisi Indonesia | 1:1 |
Jamaica