| 9. Round | 25/09/2021 | Wigan Athletic | - | Cheltenham Town | 2:0 | ||||
| 10. Round | 28/09/2021 | Sunderland AFC | - | Cheltenham Town | 5:0 | ||||
| 11. Round | 02/10/2021 | Cheltenham Town | - | Rotherham United | 0:2 | ||||
| 14. Round | 19/10/2021 | Cheltenham Town | - | Morecambe FC | 3:1 | ||||
| 15. Round | 23/10/2021 | Doncaster Rovers | - | Cheltenham Town | 3:2 | ||||
| 16. Round | 30/10/2021 | Cheltenham Town | - | Sheffield Wednesday | 2:2 | ||||
| 18. Round | 20/11/2021 | Cheltenham Town | - | Shrewsbury Town | 2:1 | ||||
| 19. Round | 23/11/2021 | Gillingham FC | - | Cheltenham Town | 0:2 | ||||
| 20. Round | 27/11/2021 | Bolton Wanderers | - | Cheltenham Town | 2:2 |
England
