1. Round | 01/08/2021 | Real Estelí FC | - | H&H Export Sébaco | 4:0 | ||||
2. Round | 10/08/2021 | UNAN Managua | - | H&H Export Sébaco | 0:2 | ||||
3. Round | 15/08/2021 | H&H Export Sébaco | - | Club Deportivo Ocotal | 0:1 | ||||
5. Round | 29/08/2021 | Juventus Managua | - | H&H Export Sébaco | 1:0 | ||||
6. Round | 03/09/2021 | ART Municipal Jalapa | - | H&H Export Sébaco | 0:2 | ||||
8. Round | 19/09/2021 | Diriangén FC | - | H&H Export Sébaco | 1:0 | ||||
9. Round | 26/09/2021 | Real Madriz | - | H&H Export Sébaco | 3:3 | ||||
10. Round | 02/10/2021 | H&H Export Sébaco | - | Real Estelí FC | 1:3 | ||||
11. Round | 10/10/2021 | H&H Export Sébaco | - | UNAN Managua | 1:1 | ||||
12. Round | 16/10/2021 | Club Deportivo Ocotal | - | H&H Export Sébaco | 1:1 | ||||
13. Round | 21/10/2021 | Managua FC | - | H&H Export Sébaco | 1:2 | ||||
14. Round | 23/10/2021 | H&H Export Sébaco | - | Juventus Managua | 3:3 | ||||
16. Round | 04/11/2021 | H&H Export Sébaco | - | ART Municipal Jalapa | 3:0 | ||||
17. Round | 17/11/2021 | H&H Export Sébaco | - | Diriangén FC | 1:1 | ||||
18. Round | 20/11/2021 | H&H Export Sébaco | - | Real Madriz | 2:3 |