| 1. Round | 11/07/2022 | Sport Boys | - | Universidad Técnica | 3:0 |  |
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| 2. Round | 17/07/2022 | Alianza Lima | - | Sport Boys | 3:1 | |
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| 3. Round | 23/07/2022 | Sport Boys | - | Universidad San Martín | 2:0 | |
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| 5. Round | 01/08/2022 | Sport Boys | - | Universidad Cesar Vallejo | 1:2 | ||||
| 6. Round | 07/08/2022 | Deportivo Municipal | - | Sport Boys | 2:2 | ||||
| 7. Round | 14/08/2022 | Sport Boys | - | Cienciano | 2:1 | |
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| 8. Round | 22/08/2022 | Deportivo Binacional | - | Sport Boys | 3:0 | |
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| 9. Round | 26/08/2022 | Sport Boys | - | AD Tarma | 2:1 |  |
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| 11. Round | 11/09/2022 | Sport Boys | - | Universitario de Deportes | 0:1 | ||||
| 12. Round | 18/09/2022 | Sport Boys | - | Academia Cantolao | 1:0 | ||||
| 13. Round | 29/09/2022 | Atlético Grau | - | Sport Boys | 3:0 | |
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| 15. Round | 09/10/2022 | Mannucci | - | Sport Boys | 0:0 | ||||
| 16. Round | 15/10/2022 | Sport Boys | - | Sporting Cristal | 3:5 | |
USA