| 1. Round | 29/07/2012 | KAA Gent | - | Lierse SK (old) | 2:0 | ||||
| 2. Round | 03/08/2012 | Lierse SK (old) | - | Standard Liège | 0:0 |  |
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| 6. Round | 01/09/2012 | Lierse SK (old) | - | Oud-Heverlee Leuven | 1:1 | ||||
| 7. Round | 15/09/2012 | Lierse SK (old) | - | RSC Anderlecht | 1:1 | ||||
| 9. Round | 29/09/2012 | Lierse SK (old) | - | SV Zulte Waregem | 1:4 | ||||
| 10. Round | 06/10/2012 | Sporting Lokeren | - | Lierse SK (old) | 2:2 | ||||
| 12. Round | 27/10/2012 | KV Mechelen | - | Lierse SK (old) | 3:0 | ||||
| 13. Round | 31/10/2012 | Lierse SK (old) | - | Club Brugge KV | 3:2 | ||||
| 14. Round | 03/11/2012 | KV Kortrijk | - | Lierse SK (old) | 4:1 | ||||
| 16. Round | 17/11/2012 | Lierse SK (old) | - | KAA Gent | 2:0 | ||||
| 18. Round | 01/12/2012 | Lierse SK (old) | - | RAEC Mons | 0:3 | ||||
| 19. Round | 09/12/2012 | KRC Genk | - | Lierse SK (old) | 4:1 |
Ghana