| 13. Round | 13/11/2021 | Warrenpoint Town | - | Cliftonville FC | 2:4 | ||||
| 14. Round | 20/11/2021 | Linfield FC | - | Cliftonville FC | 1:0 | ||||
| 15. Round | 27/11/2021 | Coleraine FC | - | Cliftonville FC | 0:0 | ||||
| 16. Round | 30/11/2021 | Larne FC | - | Cliftonville FC | 1:1 | ||||
| 17. Round | 04/12/2021 | Cliftonville FC | - | Ballymena United | 1:0 | ||||
| 18. Round | 11/12/2021 | Portadown FC | - | Cliftonville FC | 1:1 | ||||
| 19. Round | 18/12/2021 | Cliftonville FC | - | Carrick Rangers | 2:0 | ||||
| 20. Round | 04/01/2022 | Cliftonville FC | - | Crusaders FC | 0:2 | ||||
| 22. Round | 17/01/2022 | Cliftonville FC | - | Glentoran FC | 1:2 |  |
|||
| 23. Round | 21/01/2022 | Larne FC | - | Cliftonville FC | 0:1 | ||||
| 24. Round | 25/01/2022 | Cliftonville FC | - | Linfield FC | 2:2 | ||||
| 25. Round | 28/01/2022 | Ballymena United | - | Cliftonville FC | 2:2 | ||||
| 26. Round | 08/02/2022 | Carrick Rangers | - | Cliftonville FC | 2:3 | ||||
| 32. Round | 19/03/2022 | Glenavon FC | - | Cliftonville FC | 0:2 | ||||
| 28. Round | 22/03/2022 | Dungannon Swifts | - | Cliftonville FC | 0:1 | ||||
| 33. Round | 05/04/2022 | Portadown FC | - | Cliftonville FC | 0:2 |
Northern Ireland