| 14. Round | 09/01/2005 | AEK Athen | - | Panathinaikos | 1:0 | ||||
| 15. Round | 16/01/2005 | Panathinaikos | - | OFI Heraklion | 5:1 | ||||
| 16. Round | 23/01/2005 | Ionikos Nikea | - | Panathinaikos | 0:0 | ||||
| 17. Round | 30/01/2005 | Skoda Xanthi | - | Panathinaikos | 3:1 | ||||
| 18. Round | 12/02/2005 | Panathinaikos | - | Apollon Kalamarias | 5:1 | ||||
| 19. Round | 20/02/2005 | AO Egaleo | - | Panathinaikos | 0:1 | ||||
| 20. Round | 27/02/2005 | Panathinaikos | - | AO Kerkyra | 1:0 | ||||
| 21. Round | 06/03/2005 | Panionios GSS | - | Panathinaikos | 0:1 | ||||
| 23. Round | 19/03/2005 | GS Kallithea | - | Panathinaikos | 0:2 | ||||
| 24. Round | 03/04/2005 | Panathinaikos | - | Aris Saloniki | 0:0 | ||||
| 25. Round | 10/04/2005 | Panathinaikos | - | Olympiakos Piraeus | 1:0 | ||||
| 26. Round | 16/04/2005 | Ergotelis | - | Panathinaikos | 1:3 | ||||
| 27. Round | 24/04/2005 | Panathinaikos | - | Atromitos | 6:3 | ||||
| 28. Round | 08/05/2005 | PAOK Saloniki | - | Panathinaikos | 1:1 |  |
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| 29. Round | 15/05/2005 | Panathinaikos | - | AEK Athen | 0:0 | ||||
| 30. Round | 25/05/2005 | OFI Heraklion | - | Panathinaikos | 1:2 |
Cyprus