| 10. Round | 11/09/2016 | General Díaz | - | Club Olimpia | 1:2 | ||||
| 11. Round | 17/09/2016 | Club Rubio Ñu | - | General Díaz | 0:2 | ||||
| 12. Round | 24/09/2016 | General Caballero ZC | - | General Díaz | 2:2 |  |
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| 13. Round | 30/09/2016 | General Díaz | - | River Plate | 2:0 | ||||
| 14. Round | 14/10/2016 | Deportivo Capiatá | - | General Díaz | 3:0 | |
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| 16. Round | 30/10/2016 | Sol de América | - | General Díaz | 0:1 | ||||
| 17. Round | 07/11/2016 | General Díaz | - | Club Nacional | 0:2 | |
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| 18. Round | 19/11/2016 | Libertad | - | General Díaz | 2:1 | ||||
| 19. Round | 25/11/2016 | Sportivo Luqueño | - | General Díaz | 1:1 | ||||
| 20. Round | 04/12/2016 | General Díaz | - | Guaraní | 1:2 | ||||
| 21. Round | 11/12/2016 | Club Olimpia | - | General Díaz | 3:0 |
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