| 3. Round | 13/02/2015 | Deportes Tolima | - | Independiente Medellín | 1:2 |  |
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| 5. Round | 22/02/2015 | Independiente Medellín | - | La Equidad | 1:0 | ||||
| 7. Round | 28/02/2015 | Deportivo Pasto | - | Independiente Medellín | 0:3 | |
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| 8. Round | 08/03/2015 | Independiente Medellín | - | Boyacá Chicó | 1:1 | |
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| 6. Round | 25/03/2015 | Santa Fe | - | Independiente Medellín | 3:1 | ||||
| 17. Round | 26/04/2015 | Independiente Medellín | - | Atlético Junior | 1:2 | ||||
| 19. Round | 10/05/2015 | Millonarios | - | Independiente Medellín | 3:1 |  |
Colombia