| 1. Round | 06/08/2022 | RKC Waalwijk | - | FC Utrecht | 2:2 | ||||
| 2. Round | 13/08/2022 | FC Utrecht | - | SC Cambuur | 0:0 | ||||
| 3. Round | 20/08/2022 | FC Emmen | - | FC Utrecht | 3:2 | ||||
| 4. Round | 28/08/2022 | FC Utrecht | - | AFC Ajax | 0:2 | ||||
| 5. Round | 02/09/2022 | Fortuna Sittard | - | FC Utrecht | 3:4 | ||||
| 7. Round | 16/09/2022 | FC Utrecht | - | NEC Nijmegen | 0:0 | ||||
| 8. Round | 02/10/2022 | SBV Excelsior | - | FC Utrecht | 0:1 | ||||
| 9. Round | 09/10/2022 | FC Utrecht | - | AZ Alkmaar | 1:2 | ||||
| 10. Round | 16/10/2022 | PSV Eindhoven | - | FC Utrecht | 6:1 | ||||
| 11. Round | 23/10/2022 | FC Utrecht | - | Sparta Rotterdam | 3:1 |  |
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| 12. Round | 29/10/2022 | sc Heerenveen | - | FC Utrecht | 1:2 | ||||
| 13. Round | 06/11/2022 | FC Utrecht | - | FC Groningen | 2:1 | ||||
| 14. Round | 12/11/2022 | FC Volendam | - | FC Utrecht | 0:4 | ||||
| 15. Round | 08/01/2023 | FC Utrecht | - | Feyenoord | 1:1 |
Netherlands