| 10. Round | 07/11/2020 | RFC Seraing | - | Lierse Kempenzonen | 1:3 | ||||
| 9. Round | 15/11/2020 | KMSK Deinze | - | RFC Seraing | 3:0 | ||||
| 11. Round | 22/11/2020 | KVC Westerlo | - | RFC Seraing | 1:1 | ||||
| 12. Round | 29/11/2020 | RFC Seraing | - | Union Saint-Gilloise | 1:0 |  |
|||
| 16. Round | 24/01/2021 | KVC Westerlo | - | RFC Seraing | 4:3 | ||||
| 17. Round | 31/01/2021 | RFC Seraing | - | Club NXT | 2:1 | ||||
| 20. Round | 19/02/2021 | RFC Seraing | - | Union Saint-Gilloise | 0:2 | ||||
| 22. Round | 07/03/2021 | RFC Seraing | - | KVC Westerlo | 1:1 | ||||
| 23. Round | 14/03/2021 | Club NXT | - | RFC Seraing | 0:1 | ||||
| 25. Round | 03/04/2021 | Union Saint-Gilloise | - | RFC Seraing | 2:0 | |
Switzerland