| 5. Round | 27/10/2021 | GS Ilioupolis | - | Lamia | 0:3 | ||||
| Round of 16 | 02/12/2021 | Lamia | - | Ionikos Nikea | 2:0 | ||||
| Round of 16 | 23/12/2021 | Ionikos Nikea | - | Lamia | 0:1 | ||||
| Quarter-finals | 20/01/2022 | Aris Saloniki | - | Lamia | 0:0 |  |
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| Quarter-finals | 26/01/2022 | Lamia | - | Aris Saloniki | 1:0 aet | |
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| Semi-finals | 20/04/2022 | Panathinaikos | - | Lamia | 1:0 | ||||
| Semi-finals | 27/04/2022 | Lamia | - | Panathinaikos | 0:2 | |
Bolivia