| 2. Round | 27/08/2022 | PAS Giannina | - | Lamia | 1:1 |  |
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| 3. Round | 03/09/2022 | Lamia | - | Asteras Tripolis | 0:0 | ||||
| 4. Round | 12/09/2022 | PAOK Saloniki | - | Lamia | 1:0 | ||||
| 5. Round | 17/09/2022 | Atromitos | - | Lamia | 0:0 | |
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| 6. Round | 01/10/2022 | Lamia | - | Levadiakos | 1:0 | ||||
| 7. Round | 08/10/2022 | Ionikos Nikea | - | Lamia | 1:1 | |
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| 8. Round | 16/10/2022 | Lamia | - | Panathinaikos | 0:2 | |
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| 9. Round | 24/10/2022 | OFI Heraklion | - | Lamia | 0:0 | ||||
| 11. Round | 05/11/2022 | Lamia | - | Volos NFC | 2:2 | ||||
| 12. Round | 08/11/2022 | Aris Saloniki | - | Lamia | 5:0 | |
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| 14. Round | 21/12/2022 | AEK Athen | - | Lamia | 3:0 | |
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| 15. Round | 29/12/2022 | Lamia | - | PAS Giannina | 1:1 |  |
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| 16. Round | 04/01/2023 | Asteras Tripolis | - | Lamia | 3:0 | ||||
| 17. Round | 07/01/2023 | Lamia | - | PAOK Saloniki | 0:3 | ||||
| 18. Round | 14/01/2023 | Lamia | - | Atromitos | 1:1 | ||||
| 19. Round | 22/01/2023 | Levadiakos | - | Lamia | 0:0 | |
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| 20. Round | 30/01/2023 | Lamia | - | Ionikos Nikea | 0:2 | ||||
| 26. Round | 12/03/2023 | Panetolikos | - | Lamia | 1:1 |
Bolivia