| 5. Round | 03/09/2023 | Once Deportivo | - | Isidro Metapán | 2:0 | ||||
| 6. Round | 07/09/2023 | Isidro Metapán | - | Municipal Limeño | 0:3 | ||||
| 7. Round | 09/09/2023 | CD Águila | - | Isidro Metapán | 4:2 | ||||
| 8. Round | 17/09/2023 | Isidro Metapán | - | Fuerte San Francisco | 0:0 | ||||
| 9. Round | 21/09/2023 | Isidro Metapán | - | Jocoro FC | 1:1 | ||||
| 10. Round | 24/09/2023 | Alianza | - | Isidro Metapán | 1:0 | ||||
| 11. Round | 01/10/2023 | Isidro Metapán | - | FAS | 1:1 | ||||
| 12. Round | 08/10/2023 | Isidro Metapán | - | Luis Ángel Firpo | 1:1 | ||||
| 13. Round | 14/10/2023 | Santa Tecla FC | - | Isidro Metapán | 2:3 |  |
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| 14. Round | 19/10/2023 | Isidro Metapán | - | Dragón | 2:2 |  |
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| 15. Round | 22/10/2023 | Platense Zacatecoluca | - | Isidro Metapán | 1:4 | |
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| 16. Round | 29/10/2023 | Isidro Metapán | - | Once Deportivo | 2:0 | ||||
| 18. Round | 05/11/2023 | Isidro Metapán | - | CD Águila | 2:0 | |
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| 17. Round | 09/11/2023 | Municipal Limeño | - | Isidro Metapán | 1:3 | ||||
| 19. Round | 11/11/2023 | Fuerte San Francisco | - | Isidro Metapán | 1:1 | |
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| 20. Round | 15/11/2023 | Jocoro FC | - | Isidro Metapán | 2:1 | ||||
| 21. Round | 19/11/2023 | Isidro Metapán | - | Alianza | 3:1 | ||||
| 22. Round | 26/11/2023 | FAS | - | Isidro Metapán | 1:1 |
Ecuador