| 19. Round | 15/01/2006 | AFC Ajax | - | NEC Nijmegen | 1:1 | ||||
| 18. Round | 18/01/2006 | Sparta Rotterdam | - | NEC Nijmegen | 1:3 | ||||
| 20. Round | 22/01/2006 | NEC Nijmegen | - | ADO Den Haag | 5:0 |  |
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| 21. Round | 28/01/2006 | Willem II | - | NEC Nijmegen | 2:2 | |
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| 22. Round | 05/02/2006 | RKC Waalwijk | - | NEC Nijmegen | 1:3 | ||||
| 23. Round | 08/02/2006 | NEC Nijmegen | - | Feyenoord | 1:2 | ||||
| 24. Round | 12/02/2006 | FC Utrecht | - | NEC Nijmegen | 1:1 | ||||
| 25. Round | 17/02/2006 | NEC Nijmegen | - | FC Twente | 0:3 | ||||
| 26. Round | 24/02/2006 | RBC Roosendaal | - | NEC Nijmegen | 2:0 | ||||
| 27. Round | 03/03/2006 | NEC Nijmegen | - | AZ Alkmaar | 0:2 | ||||
| 28. Round | 11/03/2006 | NEC Nijmegen | - | Heracles Almelo | 2:0 | |
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| 29. Round | 18/03/2006 | PSV Eindhoven | - | NEC Nijmegen | 1:0 | |
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| 30. Round | 25/03/2006 | NEC Nijmegen | - | FC Groningen | 2:2 | |
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| 31. Round | 01/04/2006 | NEC Nijmegen | - | sc Heerenveen | 4:1 | ||||
| 32. Round | 08/04/2006 | NAC Breda | - | NEC Nijmegen | 2:1 | ||||
| 33. Round | 12/04/2006 | NEC Nijmegen | - | Roda JC Kerkrade | 0:3 | ||||
| 34. Round | 16/04/2006 | Vitesse | - | NEC Nijmegen | 1:1 |
England
Wales 
