| 2. Round | 17/08/2012 | Lille OSC | - | AS Nancy Lorraine | 1:1 | ||||
| 3. Round | 25/08/2012 | OGC Nice | - | Lille OSC | 2:2 | ||||
| 8. Round | 06/10/2012 | Lille OSC | - | AC Ajaccio | 2:0 | ||||
| 10. Round | 27/10/2012 | Lille OSC | - | Valenciennes FC | 2:1 | ||||
| 11. Round | 03/11/2012 | Évian Thonon Gaillard | - | Lille OSC | 0:2 | ||||
| 12. Round | 10/11/2012 | Lille OSC | - | Stade Brestois 29 | 1:0 | ||||
| 19. Round | 22/12/2012 | Lille OSC | - | Montpellier HSC | 4:1 | ||||
| 20. Round | 12/01/2013 | AS Nancy Lorraine | - | Lille OSC | 2:2 | ||||
| 25. Round | 15/02/2013 | Lille OSC | - | Stade Rennais | 2:0 | ||||
| 26. Round | 23/02/2013 | AC Ajaccio | - | Lille OSC | 1:3 | ||||
| 27. Round | 03/03/2013 | Lille OSC | - | Girondins Bordeaux | 2:1 | ||||
| 30. Round | 31/03/2013 | Stade Brestois 29 | - | Lille OSC | 1:2 |
Czech Republic