| 1. Round | 21/01/2023 | Lobos UPNFM | - | Motagua | 2:1 | ||||
| 3. Round | 29/01/2023 | Honduras Progreso | - | Lobos UPNFM | 0:2 | ||||
| 5. Round | 05/02/2023 | Olancho FC | - | Lobos UPNFM | 4:1 | ||||
| 7. Round | 16/02/2023 | Lobos UPNFM | - | Real España | 1:1 | ||||
| 9. Round | 25/02/2023 | Lobos UPNFM | - | Vida | 3:0 | ||||
| 11. Round | 05/03/2023 | Lobos UPNFM | - | Real Sociedad | 1:1 | ||||
| 13. Round | 19/03/2023 | Victoria | - | Lobos UPNFM | 2:0 |  |
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| 15. Round | 06/04/2023 | Marathón | - | Lobos UPNFM | 1:1 | |
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| 18. Round | 29/04/2023 | Vida | - | Lobos UPNFM | 2:1 |
Honduras