| 8. Round | 10/02/2022 | Ismaily | - | Future FC | 0:0 | ||||
| 9. Round | 16/02/2022 | Pyramids FC | - | Ismaily | 1:0 | ||||
| 10. Round | 23/02/2022 | Ismaily | - | El Gouna | 0:1 | ||||
| 11. Round | 01/03/2022 | Misr lel-Maqasah SC | - | Ismaily | 2:2 | ||||
| 12. Round | 07/03/2022 | Ismaily | - | Pharco FC | 0:0 | ||||
| 16. Round | 26/04/2022 | Ismaily | - | ENPPI | 0:2 | ||||
| 17. Round | 30/04/2022 | Tala'ea El Gaish SC | - | Ismaily | 1:0 |
Argentina