| 1. Round | 19/01/2025 | Plaza Amador | - | Sporting San Miguelito | 0:1 | ||||
| 2. Round | 25/01/2025 | Sporting San Miguelito | - | Potros del Este | 0:0 | ||||
| 4. Round | 08/02/2025 | Árabe Unido | - | Sporting San Miguelito | 2:1 | ||||
| 5. Round | 15/02/2025 | Sporting San Miguelito | - | Tauro FC | 1:0 | ||||
| 3. Round | 21/02/2025 | Alianza | - | Sporting San Miguelito | 1:2 | ||||
| 6. Round | 23/02/2025 | Sporting San Miguelito | - | Herrera FC | 2:0 | ||||
| 9. Round | 15/03/2025 | Sporting San Miguelito | - | San Francisco FC | 0:1 |  |
Panama