| 1. Round | 24/04/2022 | Club Brugge KV | - | Royal Antwerp FC | 1:0 | ||||
| 2. Round | 01/05/2022 | Royal Antwerp FC | - | Union Saint-Gilloise | 0:0 |  |
|||
| 4. Round | 12/05/2022 | RSC Anderlecht | - | Royal Antwerp FC | 2:1 | ||||
| 5. Round | 15/05/2022 | Royal Antwerp FC | - | Club Brugge KV | 1:3 | ||||
| 6. Round | 22/05/2022 | Union Saint-Gilloise | - | Royal Antwerp FC | 0:1 |
Portugal