| 7. Round | 17/09/2021 | Angoulême CFC | - | Montpellier HSC B | 3:2 | ||||
| 13. Round | 04/12/2021 | Le Puy Foot 43 | - | Montpellier HSC B | 2:0 | ||||
| 15. Round | 15/01/2022 | Vendée Les Herbiers | - | Montpellier HSC B | 2:1 | ||||
| 18. Round | 12/02/2022 | US Colomiers | - | Montpellier HSC B | 1:1 | ||||
| 25. Round | 16/04/2022 | Montpellier HSC B | - | Stade Montois | 4:0 | ||||
| 27. Round | 30/04/2022 | Montpellier HSC B | - | Le Puy Foot 43 | 1:3 | ||||
| 28. Round | 14/05/2022 | Angers SCO B | - | Montpellier HSC B | 1:0 |
France