| 1. Round | 14/08/2021 | NK Dubrava | - | NK Rudeš | 2:2 | ||||
| 2. Round | 21/08/2021 | NK Rudeš | - | HNK Orijent Rijeka | 2:2 | ||||
| 3. Round | 27/08/2021 | HNK Cibalia | - | NK Rudeš | 2:1 |  |
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| 6. Round | 18/09/2021 | NK Rudeš | - | NK BSK Bijelo Brdo | 3:1 | ||||
| 7. Round | 25/09/2021 | Dinamo Zagreb II | - | NK Rudeš | 0:0 | ||||
| 8. Round | 02/10/2021 | NK Rudeš | - | NK Solin | 1:0 | ||||
| 9. Round | 17/10/2021 | NK Croatia Zmijavci | - | NK Rudeš | 1:0 | ||||
| 10. Round | 23/10/2021 | NK Rudeš | - | NK Opatija | 3:0 | ||||
| 11. Round | 31/10/2021 | NK Varaždin | - | NK Rudeš | 2:1 | ||||
| 12. Round | 07/11/2021 | NK Osijek II | - | NK Rudeš | 2:1 | ||||
| 15. Round | 04/12/2021 | NK Rudeš | - | NK Dugopolje | 4:0 | ||||
| 16. Round | 12/02/2022 | NK Rudeš | - | NK Dubrava | 4:1 | ||||
| 17. Round | 19/02/2022 | HNK Orijent Rijeka | - | NK Rudeš | 0:1 | ||||
| 19. Round | 04/03/2022 | NK Inter Zaprešić | - | NK Rudeš | 1:0 | ||||
| 22. Round | 02/04/2022 | NK Rudeš | - | Dinamo Zagreb II | 3:2 |  |
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| 23. Round | 09/04/2022 | NK Solin | - | NK Rudeš | 1:2 | ||||
| 24. Round | 16/04/2022 | NK Rudeš | - | NK Croatia Zmijavci | 2:0 | |
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| 26. Round | 30/04/2022 | NK Rudeš | - | NK Varaždin | 3:0 | |
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| 27. Round | 07/05/2022 | NK Rudeš | - | NK Osijek II | 1:0 | |
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| 28. Round | 13/05/2022 | NK Jarun | - | NK Rudeš | 1:1 |
Croatia