| 5. Round | 14/08/2021 | TSC Bačka Topola | - | FK Radnički 1923 | 4:4 | ||||
| 6. Round | 21/08/2021 | Crvena Zvezda | - | TSC Bačka Topola | 3:1 | ||||
| 7. Round | 27/08/2021 | TSC Bačka Topola | - | Mladost Lučani | 2:1 |  |
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| 8. Round | 10/09/2021 | Spartak Subotica | - | TSC Bačka Topola | 0:0 | ||||
| 9. Round | 16/09/2021 | TSC Bačka Topola | - | FK Napredak | 1:2 | ||||
| 16. Round | 05/11/2021 | FK Novi Pazar | - | TSC Bačka Topola | 1:1 | ||||
| 18. Round | 28/11/2021 | FK Kolubara | - | TSC Bačka Topola | 2:1 | ||||
| 19. Round | 06/12/2021 | TSC Bačka Topola | - | Radnički Niš | 1:1 | ||||
| 20. Round | 11/12/2021 | FK Radnički 1923 | - | TSC Bačka Topola | 0:3 | ||||
| 21. Round | 16/12/2021 | TSC Bačka Topola | - | Crvena Zvezda | 2:3 |
Serbia