| Group 1 | 07/03/2021 | FAS | - | Isidro Metapán | 0:1 | ||||
| Group 1 | 11/03/2021 | Sonsonate FC | - | FAS | 2:1 |  |
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| Group 1 | 14/03/2021 | FAS | - | Once Municipal | 0:0 | ||||
| Group A | 20/03/2021 | Atlético Marte | - | FAS | 1:1 |  |
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| Group A | 01/04/2021 | FAS | - | Alianza | 3:2 | |
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| Group A | 04/04/2021 | Once Municipal | - | FAS | 3:1 | ||||
| Group A | 07/04/2021 | FAS | - | Luis Ángel Firpo | 3:1 | |
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| Group A | 18/04/2021 | FAS | - | Atlético Marte | 4:3 | ||||
| Group A | 22/04/2021 | Alianza | - | FAS | 1:1 | ||||
| Group A | 25/04/2021 | FAS | - | Once Municipal | 2:3 | ||||
| Group A | 28/04/2021 | Luis Ángel Firpo | - | FAS | 0:0 | ||||
| Group A | 01/05/2021 | FAS | - | Jocoro FC | 1:0 | ||||
| Quarter-finals | 05/05/2021 | FAS | - | Municipal Limeño | 2:1 | |
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| Semi-finals | 16/05/2021 | Santa Tecla FC | - | FAS | 0:1 | |
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| Semi-finals | 23/05/2021 | FAS | - | Santa Tecla FC | 4:2 pso | ||||
| Final | 30/05/2021 | Alianza | - | FAS | 3:4 pso |
USA