| 1. Round | 10/07/2022 | Atlético Huila | - | Valledupar FC | 3:2 | ||||
| 2. Round | 16/07/2022 | Llaneros FC | - | Atlético Huila | 3:2 | ||||
| 3. Round | 22/07/2022 | Atlético Huila | - | Real Cartagena | 2:3 | ||||
| 5. Round | 04/08/2022 | Atlético Huila | - | Fortaleza FC | 1:2 | ||||
| 7. Round | 16/08/2022 | Atlético Huila | - | Boyacá Chicó | 1:1 | ||||
| 8. Round | 24/08/2022 | Tigres FC | - | Atlético Huila | 1:2 | ||||
| 12. Round | 13/09/2022 | Leones FC | - | Atlético Huila | 2:2 |  |
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| 13. Round | 18/09/2022 | Atlético Huila | - | Bogotá FC | 2:0 | ||||
| 14. Round | 28/09/2022 | Deportes Quindío | - | Atlético Huila | 1:1 | ||||
| 16. Round | 08/10/2022 | Atlético Huila | - | Atlético FC | 6:0 |
Colombia