| 7. Round | 03/09/2022 | Leyton Orient | - | Tranmere Rovers | 2:0 | ||||
| 9. Round | 13/09/2022 | Tranmere Rovers | - | Bradford City | 1:2 | ||||
| 10. Round | 17/09/2022 | Salford City | - | Tranmere Rovers | 0:1 | ||||
| 11. Round | 24/09/2022 | Walsall FC | - | Tranmere Rovers | 0:1 | ||||
| 12. Round | 01/10/2022 | Tranmere Rovers | - | Barrow AFC | 1:0 | ||||
| 14. Round | 08/10/2022 | Sutton United | - | Tranmere Rovers | 0:2 | ||||
| 15. Round | 14/10/2022 | Tranmere Rovers | - | Crewe Alexandra | 3:0 |  |
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| 16. Round | 22/10/2022 | Harrogate Town | - | Tranmere Rovers | 1:1 | ||||
| 13. Round | 25/10/2022 | Tranmere Rovers | - | Rochdale AFC | 1:1 |  |
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| 17. Round | 29/10/2022 | Tranmere Rovers | - | Carlisle United | 0:2 | ||||
| 8. Round | 01/11/2022 | Tranmere Rovers | - | Stockport County | 0:0 | ||||
| 18. Round | 12/11/2022 | Swindon Town | - | Tranmere Rovers | 1:1 | |
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| 19. Round | 19/11/2022 | Tranmere Rovers | - | AFC Wimbledon | 0:2 |  |
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| 24. Round | 29/12/2022 | Barrow AFC | - | Tranmere Rovers | 1:2 |
Cameroon