| 5. Round | 17/03/2021 | UD Universitario | - | Herrera FC | 4:0 | ||||
| 8. Round | 28/03/2021 | Herrera FC | - | Tauro FC | 1:1 | ||||
| 12. Round | 22/04/2021 | Independiente de La Chorrera | - | Herrera FC | 1:3 | ||||
| 14. Round | 29/04/2021 | Veraguas Club Deportivo | - | Herrera FC | 0:0 | ||||
| 16. Round | 08/05/2021 | Herrera FC | - | UD Universitario | 2:0 |
Panama