| 4. Round | 19/02/2023 | Tacuary | - | General Caballero DJLM | 1:1 | ||||
| 5. Round | 26/02/2023 | General Caballero DJLM | - | Sportivo Trinidense | 1:4 | ||||
| 6. Round | 03/03/2023 | Guaireña FC | - | General Caballero DJLM | 0:0 | ||||
| 7. Round | 12/03/2023 | General Caballero DJLM | - | Club Olimpia | 1:2 | ||||
| 8. Round | 20/03/2023 | General Caballero DJLM | - | Cerro Porteño | 2:3 | ||||
| 9. Round | 31/03/2023 | Libertad | - | General Caballero DJLM | 1:0 | ||||
| 10. Round | 03/04/2023 | General Caballero DJLM | - | Sportivo Ameliano | 0:1 | ||||
| 11. Round | 11/04/2023 | Guaraní | - | General Caballero DJLM | 3:1 | ||||
| 12. Round | 15/04/2023 | Resistencia SC | - | General Caballero DJLM | 1:1 | ||||
| 16. Round | 07/05/2023 | Sportivo Trinidense | - | General Caballero DJLM | 2:0 |
Paraguay
Mexico