| 2. Round | 12/08/2021 | Victoria | - | Motagua | 0:1 | ||||
| 3. Round | 15/08/2021 | Victoria | - | Real Sociedad | 0:2 | ||||
| 4. Round | 22/08/2021 | Honduras Progreso | - | Victoria | 2:0 | ||||
| 5. Round | 26/08/2021 | Vida | - | Victoria | 2:0 | ||||
| 7. Round | 04/09/2021 | Lobos UPNFM | - | Victoria | 3:0 | ||||
| 8. Round | 12/09/2021 | Victoria | - | Marathón | 1:0 | ||||
| 9. Round | 16/09/2021 | Victoria | - | Platense | 2:0 | ||||
| 12. Round | 03/10/2021 | Motagua | - | Victoria | 5:0 |
Honduras